Endothelium-derived relaxing factor in brain blood vessels is not nitric oxide.

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Endothelium-derived relaxing factor in brain blood vessels is not nitric oxide.

BACKGROUND The endothelium-derived relaxing factor that mediates the actions of acetylcholine is now most frequently identified as nitric oxide. Nitric oxide is believed to have numerous important regulating actions in neurons, blood vessels, and several other biological systems. SUMMARY OF REVIEW The literature concerning tissue other than cerebral blood vessels supports the conclusion that ...

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Comments, Opinions, and Reviews Endothelium-Derived Relaxing Factor in Brain Blood Vessels Is Not Nitric Oxide

Background: The endothelium-derived relaxing factor that mediates the actions of acetylcholine is now most frequently identified as nitric oxide. Nitric oxide is believed to have numerous important regulating actions in neurons, blood vessels, and several other biological systems. Summary of Review: The literature concerning tissue other than cerebral blood vessels supports the conclusion that ...

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The Possible Involvement of Nitric Oxide/Endothelium Derived Relaxing Factor in Atropine-Induced Vasorelaxation

Atropine has been used to block cholinergic neurotransmission in basic research. Large doses of atropine cause vasodilation of the blood vessels in the skin. This effect is apparently unconnected with the antimuscarinic activity of atropine and seems to be due to a direct action on the blood vessels. It has been suggested that atropine blocks muscarinic receptors at low doses and it induces th...

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The identification of nitric oxide as endothelium-derived relaxing factor.

The identification of endothelium-derived relaxing factor as nitric oxide (NO) dramatically altered the course of vascular biology, as well as other biomedical disciplines. The ubiquity of this natural product of cell metabolism and the complexity of its biochemistry provide a rich source of molecular mediators of phenotype in health and disease.

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the possible involvement of nitric oxide/endothelium derived relaxing factor in atropine-induced vasorelaxation

atropine has been used to block cholinergic neurotransmission in basic research. large doses of atropine cause vasodilation of the blood vessels in the skin. this effect is apparently unconnected with the antimuscarinic activity of atropine and seems to be due to a direct action on the blood vessels. it has been suggested that atropine blocks muscarinic receptors at low doses and it induces the...

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ژورنال

عنوان ژورنال: Stroke

سال: 1992

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.23.10.1527